Effect of Intravenous Dexmedetomidine on Analgesic Duration of Infraclavicular Block

• Status: Completed
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will evaluate the effect of Dexmedetomidine sedation on the duration of infraclavicular block in patients scheduled for surgery of elbow, forearm and/or hand. All patients will receive infraclavicular block before the surgery and then they will be randomized to receive either Dexmedetomidine or Propofol sedation. Duration of the sensory block will be evaluated in recovery room, 24 and 48 hours after the surgery.

Hypothesis:

Primary: Dexmedetomidine sedation increases the duration of sensory infraclavicular block in patients scheduled for upper limb surgery.

Secondary: Dexmedetomidine sedation

• Gives an adequate level of sedation during the surgical procedure

• Reduces the requirements of postoperative opioids

• Improves the quality of sleep on the night of the surgery

• Increases patients satisfaction regarding the anesthesia technique

• Dexmedetomidine sedation is safe and easy to use

• Dexmedetomidine sedation provides less respiratory depression during the procedure.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Analgesics; Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

• Male and females of 16-80 years of age, scheduled for hand, forearm and elbow ambulatory surgery with an infraclavicular block.

• American Society of Anesthesiologist (ASA) Class I, II, III

• Ability to cooperate with study related procedures

Exclusion Criteria:

• ASA IV

• Narcotic dependent (opioid intake more than 3 months) or chronic pain conditions

• Associated significant cardiac or respiratory disease, neurological deficits

• Coexisting hematological disorder or with deranged coagulation

• Pre-existing major organ dysfunction

• Psychiatric illnesses

• Emergency surgery

• Lack of informed consent

• Allergy to any of the drugs used in the study

• Surgical procedure duration greater than 3 hours