Effect of Intravenous Dynastat on Postoperative Sore Throat
Status:
Unknown status
Trial end date:
2020-11-30
Target enrollment:
Participant gender:
Summary
A postoperative sore throat (POST) after tracheal intubation is one of the most common
postoperative problems causing dissatisfaction to participants, including sore throat, dry
throat, cough, sputum, hoarseness and even dysphagia. Both nonpharmacological and
pharmacological measures have been attempted to alleviate the incidence and severity of POST
with variable success. Airway inflammation may be important in the pathogenesis of these
symptoms in intubated participants but however, there was still no study to investigate the
effect of cyclooxygenase-2 (COX-2) for the prevention of POST. So, the investigators' study
will be the first one to investigate if perioperatively intravenous (IV) Dynastat injection
can be used as a new indication for POST prevention.