Effect of Intravenous Lidocaine on Immediate Post-operative Pain, Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Placebo Controlled Trial

• Status: Recruiting
• Trial end date: 2020-11-24
• Target enrollment: 0
• Participant gender: All

Summary

Lidocaine is a drug that has multiple uses. One of these is that when intravenously administered it is effective in reducing post-operative pain. The aim of this study is to investigate the beneficial effects of intravenous lignocaine on reducing pain, nausea and vomiting after laparoscopic cholecystectomy. Also, by this research, we are aiming to find a suitable alternative analgesic.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aga Khan University Hospital, Pakistan
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Elective laparoscopic cholecystectomy

• All adults aged between 18 to 65 years

• ASA I and II

Exclusion criteria:

• BMI greater than 35kg/m2

• Allergy to local anesthetic agents

• Patient with or history of arrhythmias

• Patients with SGPT greater than 35 IU/L for females and greater than 45 IU/L for males.

• Patients with chronic renal disease and creatinine greater than 1.5mg/dl.

• Chronic use of opioids

• The surgeries which were converted to open procedures.