Effect of Intravenous Nalbuphine on Emergence Agitation

• Status: Completed
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Our primary objective of this study is to compare the effect of administration of single dose of intravenous nalbuphine given with induction of anesthesia with intravenous nalbuphine given at the end of surgery on the incidence and severity of EA in children undergoing repair of rupture globe under general anesthesia.

The secondary outcomes will include FLACC score for postoperative pain assessment, hemodynamic variables, any complications as postoperative vomiting (POV) and sedation and parents' satisfaction score.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Anesthetics; Nalbuphine

Criteria

Inclusion Criteria:

• Age: 3-8 years.

• American Society of Anesthesiologists (ASA) physical status I-II scheduled to undergo repair of rupture globe.

• Gender: both.

Exclusion Criteria:

• Parent refusal.

• History of developmental delay or mental retardation.

• Known hypersensitivity to any drug used in this study.

• Children with co-morbid conditions like congenital heart disease, respiratory pathology and central nervous system disorders.