Overview

Effect of Isosorbide Mononitrate on Hypertension to Improve Left Ventricular Hypertrophy, Fibrosis and Myocardial Function

Status:
Withdrawn
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to test whether treatment with isosorbide mononitrate will improve left ventricular hypertrophy ("thickening") which puts people at risk for developing heart failure. Once it develops, heart failure is a very serious condition and thus it is important to find ways to prevent it from happening. The investigators have reasons to believe that dilating the blood vessels with this specific medication will improve the thickening of the heart, which increases the risk of heart failure.
Phase:
Phase 2
Details
Lead Sponsor:
Corporal Michael J. Crescenz VA Medical Center
Treatments:
Isosorbide
Isosorbide Dinitrate
Isosorbide-5-mononitrate