Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

Prevalence of chronic pain after mastectomy is beyond 50% 3 months after surgery. This pain is related to a sensitization of the central nervous system through N-methyl-D-asparate (NMDA) receptors. Ketalar might prevent the occurrence of chronic pain by anti-NMDA properties after mastectomy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospices Civils de Lyon
• Treatments: Ketamine

Criteria

Inclusion Criteria:

• Mastectomy in patients 18 to 80 years old

Exclusion Criteria:

• American Society of Anesthesiology (ASA) class >= 3

• Renal, heart or hepatic failure

• Allergy to ketalar

• Psychiatric disease

• Chronic antalgic treatment