Effect of Ketamine Assisted Analgesia on Oxygen Supply and Oxygen Consumption in Patients After Cardiac Surgery
Status:
Recruiting
Trial end date:
2022-05-01
Target enrollment:
Participant gender:
Summary
After cardiopulmonary bypass heart surgery, with the rewarming of body temperature, the
metabolic capacity of the body is enhanced, the microcirculation is opened, and tissue
perfusion is increased. At the same time, the body pays off the oxygen debt formed by the low
temperature and reduced blood flow in cardiopulmonary bypass, so that the tissue oxygen
demand increases and oxygen consumption increases.Analgesia and sedation are important
treatment measures for patients after cardiopulmonary bypass. S-isomer of ketamine and
eselamine enhanced the sedation and enhanced the analgesic effect, but whether it can improve
the imbalance of oxygen supply and oxygen consumption after cardiopulmonary bypass is
unknown.