Overview

Effect of Ketamine Assisted Analgesia on Oxygen Supply and Oxygen Consumption in Patients After Cardiac Surgery

Status:
Recruiting

Trial end date:
2022-05-01

Target enrollment:
0

Participant gender:
All

Summary

After cardiopulmonary bypass heart surgery, with the rewarming of body temperature, the metabolic capacity of the body is enhanced, the microcirculation is opened, and tissue perfusion is increased. At the same time, the body pays off the oxygen debt formed by the low temperature and reduced blood flow in cardiopulmonary bypass, so that the tissue oxygen demand increases and oxygen consumption increases.Analgesia and sedation are important treatment measures for patients after cardiopulmonary bypass. S-isomer of ketamine and eselamine enhanced the sedation and enhanced the analgesic effect, but whether it can improve the imbalance of oxygen supply and oxygen consumption after cardiopulmonary bypass is unknown.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

First People's Hospital of Chenzhou

Treatments:

Ketamine

Criteria

Inclusion Criteria:

- Consecutive adult (>18years)patients after heart surgery

Exclusion Criteria:

- Chronic kidney disease (CKD); ECMO or IABP assistance is required; Malignant tumor;
Acquired immunodeficiency syndrome; receive psychiatric medication.