Effect of Ketamine in Depressive Symptoms of Elderly Patients With Visual Impairment.

• Status: Completed
• Trial end date: 2018-07-30
• Target enrollment: 0
• Participant gender: All

Summary

the prevalence of depression in elderly is from 4 to 30% and is associated with a lower quality of life mayor medical comorbidity, and increased mortality. Although there are various treatments for depression in the elderly, the study of interventions in resistant depression is limited and there are few reports of the efficacy and safety profile of alternative interventions such as ketamine in the elderly. The final objective of the present study is to report the effects of a single infusion of ketamine on the depressive symptoms in patients undergoing ophthalmologic surgery

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Instituto Mexicano del Seguro Social
• Collaborator: Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
• Treatments: Ketamine

Criteria

Inclusion Criteria:

• Men and women aged 60 years or older who due to the severity of visual disability required to be operated on for eye surgery using retrobulbar block

• Intraocular pressure <20 mm Hg and

• ASA functional capacity from I to III

Exclusion Criteria:

• Previous antidepressants medications

• Cognitive impairment was found according to the Short Portable Mental Status Questionnaire (SPMSQ) assessment

• In case of a history of psychosis, schizophrenia, nephropathy

• They had a history of difficulties to control arterial blood pressure, uncontrolled hepatic disorders or had a history of adverse response to ketamine according clinical records