Effect of Ketoconazole on Sufentanil NanoTab Pharmacokinetics

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Evaluate the effect of taking ketoconazole on sufentanil plasma concentrations following sublingual administration of sufentanil NanoTab.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: AcelRx Pharmaceuticals, Inc.
• Treatments: Dsuvia; Ketoconazole; Sufentanil

Criteria

Inclusion Criteria:

• Non smoking

• Ages 18 to 45 year, inclusive

• BMI between 18 and 30

Exclusion Criteria:

• subjects taking any prescription or OTC medications or vitamins or supplements

• pregnant females

• subjects with pulmonary disease or sleep apnea