Effect of Ketoconazole on the Pharmacokinetics of Vinflunine

• Status: Completed
• Trial end date: 2007-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to test how ketoconazole affects with handling of vinflunine by the body which might affect how much vinflunine is in the blood stream and for how long

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bristol-Myers Squibb
• Treatments: Ketoconazole; Vinblastine

Criteria

Inclusion Criteria:

• Advanced cancer excluding cancer within the blood, adequate kidney and liver function.

Exclusion Criteria:

• Prior use of vinflunine, other active medical disorders, severe nerve damage