Effect of Lacidipine and Losartan on 24 Hour Systolic Blood Pressure Variability in Elderly Hypertensive Patients

• Status: Unknown status
• Trial end date: 2008-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to evaluate the effect of lacidipine and losartan in elderly hypertensive patients on reducing the 24 hour systolic BP variability, which is one of the potential parameter to consider in treating elderly hypertensive patients.

• Phase: Phase 4

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Lacidipine; Losartan

Criteria

Inclusion Criteria:

• Elderly patients (age > 65 years)

• Essential hypertension (systolic BP > 140 mmHg or diastolic BP > 90 mm Hg)

• Provide written informed content

Exclusion Criteria:

• Secondary hypertension

• Myocardial infarction or cerebrovascular accident within the preceding 6 months

• Clinically significant valvular heart disease, heart failure (Class III, IV), renal insufficiency (serum creatinine > 2.5mg/dl), hepatic failure, uncontrolled diabetes mellitus

• Known hypersensitivity to the drugs used in the study.