Effect of Lifitegrast on Dry Eye Disease Signs and Symptoms

• Status: Completed
• Trial end date: 2018-03-15
• Target enrollment: 0
• Participant gender: All

Summary

To determine whether a fall in tear osmolarity precedes improvement in symptoms and signs of dry eye in dry eye patients treated topically with 5% lifitegrast drops for 3 months.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lifelong Vision Foundation
• Treatments: Lifitegrast; Ophthalmic Solutions

Criteria

Inclusion Criteria:

• Tear Osmolarity > 320 mOsm/L

• VAS eye dryness > 40

• No other ocular pathology

• No contact lens wear

• Not currently on T cell modulator

• No change in therapy in last 2 months

• Willingness to adhere to therapy and study visits

• Patients qualified for prescription of lifitegrast drops

Exclusion Criteria:

• Contact lens use

• Eye surgery in Past 6 months

• Use of tear supplements in past 2 hours