Effect of Medium Chain Triglyceride Intake on Colonization of Preterm Infants With Candida

• Status: Active, not recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates whether adding a dietary supplement similar to coconut oil (MCT oil) to feedings in premature infants will reduce the amount of yeast (Candida) detectable in their stool. Infants who have Candida in their stool are eligible to participate. Half of the enrolled infants will have additional MCT oil added to their feedings and half will not.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Joseph Bliss
• Collaborator: Tufts University

Criteria

Inclusion Criteria:

• Premature infant admitted to the Neonatal Intensive Care Unit at Women & Infants Hospital

• Receiving full enteral feeds of either preterm or transitional formula or fortified breast milk

• Anticipated to have a minimum stay of two weeks

Exclusion Criteria:

• Prior exposure to antifungal drugs