Effect of Memantine on Cognitive Impairment in Patients With Epilepsy

• Status: Completed
• Trial end date: 2020-01-15
• Target enrollment: 0
• Participant gender: All

Summary

Evaluate the efficacy of memantine on improving the cognitive impairment in patient with epilepsy

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Memantine

Criteria

Inclusion Criteria:

• Patients with idiopathic epilepsy.

• Normal brain imaging (CT brain).

• Patients on anti epileptic drugs more than 6 months.

• No more than two fits per month.

• Score of Mini mental state examination (10-24), mild and moderate cognitive impairment.

• No other medical disorders.

Exclusion Criteria:

• Progressive neurological diseases.

• Abnormal brain imaging (CT brain).

• More than two fits per month.

• Patients with severe cognitive impairment, score of MMSE less than10.

• Patients with severe medical disorders