Effect of Midazolam Premedication on Mask Ventilation Difficulty
Status:
Not yet recruiting
Trial end date:
2022-10-15
Target enrollment:
Participant gender:
Summary
Mask ventilation has great importance during anesthesia induction because it is the only way
to oxygenate patients who have lost consciousness and spontaneous breathing. Adequate muscle
relaxation and depth of anesthesia may assist with mask ventilation. It is known that
premedication to reduce anxiety has a relaxing effect on airway muscles. Midazolam is
frequently used in premedication because it has a rapid onset of action and does not cause
hemodynamic changes. In addition, midazolam may relax the airway by acting directly on the
airway smooth muscle and thus facilitate mask ventilation during anesthesia induction. In
this study, we will conduct a randomized controlled trial to evaluate the effect of midazolam
premedication on facilitating mask ventilation in children.