Effect of Morning Versus Evening Perindopril on Blood Pressure Control in People With Type 2 Diabetes

• Status: Completed
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

We assessed the influence of time of administration of ACE inhibitors on circadian blood pressure control in sub Saharan type 2 diabetes patients with stage 1 hypertension over 56 days as first line treatment.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yaounde Central Hospital
• Collaborator: University of Yaounde 1
• Treatments: Perindopril

Criteria

Inclusion Criteria:

• Type 2 diabetes

• Grade 1 hypertension

• Informed consent

Exclusion Criteria:

• estimated creatinine clearance≤ 60ml/min

• White coat hypertension after initial 24 hour ABPM

• Previous antihypertensive treatment

• Pregnant women

• Individuals working during the night

• Hyperkalemia