Effect of Morphine, Tramadol, and Ketorolac on Postoperative Stress and Immune Responses

• Status: Unknown status
• Trial end date: 2015-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

Comparison between the effects of intravenous morphine, tramadol and ketorolac on stress and immune responses in patients undergoing modified radical mastectomy

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Ketorolac; Ketorolac Tromethamine; Morphine; Tramadol

Criteria

Inclusion Criteria:

• patients aged (20-60 years)

• weighting (50 -75 Kg),

• with American Society of Anesthesiologists (ASA) physical status I or II

Exclusion Criteria:

• Patients with known allergy to opioids or NSAIDS,

• gastric or duodenal ulcer, on radiotherapy or chemotherapy

• received blood transfusion before the surgery or preoperative NSAIDs, steroid or opioid medications 48 hours prior to operation