Effect of NAC on Sleep Apnea

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Sleep studies in ESRD patients have identified increased prevalence of Sleep Apnea. Based on current knowledge, treatment aimed at reducing oxidative stress might improve Sleep Apnea in HD patients. The aim of our study is to investigate the effect of N-acetylsysteine on Sleep Apnea in HD patients.

• Phase: N/A

Details

• Lead Sponsor: Assaf-Harofeh Medical Center
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• The study will include 20 patients with ESRD, treated with chronic hemodialysis in Assaf Harofeh Medical Center and suffering from sleep disturbances, such as frequent arousals, snoring, daytime sleepiness.

Exclusion Criteria:

Patients will be excluded from the study if they are:

• Recently started treated with chronic dialysis: less than 3 months.

• Survived recent major illness, requiring hospitalisation in the last 3 months.

• Patients with acute renal failure

• Currently treated with antioxidants ( NAC, vitamin E ets.)

• Current use of sleep pills