Effect of Oral 5-HTP Intake on Urinary 5-HIAA Excretion

• Status: Terminated
• Trial end date: 2005-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a research study looking at the effect of 5-Hydroxy Tryptophan (5-HTP) on urine excretion of 5-Hydroxyindolacetic acid (5-HIAA). 5-HTP is a common over the counter product that is sold in natural food stores and via the Internet. Increased levels of 5-HIAA in the urine can be found in a specific type of cancer, called carcinoid tumor. This study will examine the effect of oral 5-HTP intake on 5-HIAA excretion. Understanding this effect may help to determine which tests should be done in a patient with increased 5-HIAA excretion who's also taking 5-HTP.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Western Ontario, Canada
• Treatments: Serotonin

Criteria

Inclusion Criteria:

• 18 years and older

• in good health

Exclusion Criteria:

• Pregnancy

• Intake of drugs that affect 5-HIAA excretion in urine

• Anti-depressants

• Participation in other studies