Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients
Status:
Completed
Trial end date:
2007-12-01
Target enrollment:
Participant gender:
Summary
Oropharyngeal bacteria play an important role in the pathogenesis of nosocomial pneumonia in
critically ill patients. Oral cleansing with chlorhexidine has been shown to decrease
incidence of pneumonia in patients undergoing open heart surgery. Its role in critically ill
general ICU patients is not yet proven. The present study proposes to study the effectiveness
of twice-daily oral cleansing with 0.2% chlorhexidine solution on the incidence of nosocomial
pneumonia in ICU patients admitted to a single intensive care unit of an Indian public
hospital