Effect of Oral Phloroglucin (Flospan®) as Premedication of Non-sedative Diagnostic Esophagogastroduodenoscopy
Status:
Completed
Trial end date:
2017-12-29
Target enrollment:
Participant gender:
Summary
Gastric peristalsis, which occurs during the endoscopic procedure, limits the visual
inspection of the inspection field, causing interference in the inspection. The actual
endoscopic examination is most commonly used by injecting Hyoscine butylbromide(Buscopan®),
Cimetropium bromide (Algiron ®) into intravenous or muscular injection so it is not suitable
for patients who undergo non-sedative esophagogastroduodenoscopy. In addition, these drugs
were reported the side effects including thirst, dysuria, transient visual filed defect,
tachycardia, anxiety so were not recommended for benign prostate hyperplasia, glaucoma, old
age patients. For comfort and succesfull test, anti-spasmodics which don't have
anti-cholinergic effect and are possible to take orally is necessary. Phloroglucin(Flospan®)
is a smooth muscle relaxant that is currently used in the anti-spasmodic treatment without
anticholinergic action so it can be administered in patients with glaucoma or BPH. Also it is
suitable for endoscopic premedication due to transparent liquid component. Therefore, in this
study, we would like to confirm the efficacy and safety of Phloroglucin (Flospan ®), which
can be taken orally, as an pre-medication for non-sedative endoscopy.