Effect of Oral Supplementation With Curcumin on Insulin Sensitivity in Subjects With Prediabetes

• Status: Unknown status
• Trial end date: 2020-02-28
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the effects of oral supplementation with curcumin on the insulin sensitivity in subjects with prediabetes. The half of participants will receive curcumin and bioperine in combination, while the other half receive placebo.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hospital General de México Dr. Eduardo Liceaga
• Treatments: Curcumin; Insulin

Criteria

Inclusion Criteria:

• Men and women with age between 18 and 60 years old.

• With prediabetes diagnosis, according to the American Diabetes Association :

1. Fasting serum glucose: 100-125 mg/dL

2. Glycosylated hemoglobin (HbA1c): 5.7-6.4%

3. Post-prandial glucose: 140-199 mg/dL after an oral dose of 75 g of glucose.

Exclusion Criteria:

• Subjects with any type of diabetes.

• Subjects with body mass index > 35 kg/m2

• Pregnant Women.

• Volunteers who ingest drugs that alter blood glucose levels, antiplatelet agents, angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, fibrates, statins.

• Subjects with serum creatinine > 2 mg/dL or in renal replacement therapy.

• Subjects that normally consume food supplements.

• Subjects with acute infections or with chronical diseases (cancer, rheumatoid arthritis, etc.).