Effect of PDE5 Inhibition on Adipose Metabolism in Humans
Status:
Recruiting
Trial end date:
2025-12-01
Target enrollment:
Participant gender:
Summary
This is a randomized, double-blinded, placebo-controlled study of the effects of PDE5
inhibition with tadalafil on adipose tissue in obese individuals. Adipose metabolism will be
measured using magnetic resonance imaging (MRI) scans and by aspirating a small amount of
adipose to measure gene expression.