Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage

• Status: Active, not recruiting
• Trial end date: 2021-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators are conducting a study on pain control for dilation and curettage (D&C). Participants are eligible to enroll if they are a planning to have a D&C in a participating clinic. The investigators are studying how different ratios of medication to liquid affect pain when injected around the cervix. Both potential methods use the same dose of medication, though researchers would like to know which one works better. To be in this study, participants must be over the age of 18 with an early pregnancy loss or undesired pregnancy measuring less than 12 weeks gestation undergoing D&C while awake in clinic.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of California, San Diego
• Collaborators: Society of Family Planning; University of California, Los Angeles
• Treatments: Arginine Vasopressin; Lidocaine; Vasopressins

Criteria

Inclusion Criteria:

1. Women over the age of 18 presenting to University of California, San Diego (UCSD) and University of California, Los Angeles (UCLA)

2. Undesired pregnancy or missed abortion < 11 weeks 6 days gestation

3. Must speak English or Spanish

4. Desire surgical termination of pregnancy or management of miscarriage in clinic

Exclusion criteria:

1. Women with a diagnosis of inevitable or incomplete abortion

2. Desire for general anesthesia or IV sedation

3. Chronic pain conditions

4. Any medical comorbidities that are a contraindication to performing the procedure in the clinic setting

5. Allergy to or refusal of ketorolac, oral Versed, or a paracervical block

6. If they have taken any pain medications the day of presentation to clinic

7. If they have taken Misoprostol the day of presentation to clinic