Effect of Paracetamol,Pregabalin and Dexamethasone on Pain and Opioid Requirements in Postoperative Patients

• Status: Completed
• Trial end date: 2008-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

Women scheduled for abdominal hysterectomy needs postoperative pain treatment, i.e. morphine. Unfortunately morphine has side-effect: nausea, vomiting, sedation and dizziness, which is unpleasant for the patients and sometimes keeps them at bed longer time than needed. We investigate in new combinations of analgesics for postoperative pain, hoping to minimize the need for morphine.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Glostrup University Hospital, Copenhagen
• Treatments: Acetaminophen; BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Pregabalin

Criteria

Inclusion Criteria:

• Women scheduled for abdominal hysterectomy, between the age of 18 and 75, ASA 1-2

• BMI between 18-32.

Exclusion Criteria:

Patients who:

• Are unable to cooperate

• Has cancer ovarian

• Does not speak Danish

• Has allergy for drugs used in the trial

• Has drug and medicine abuse

• Epilepsy

• Diabetes treated with medicine

• Chronic pain condition

• Daily use of antacids or analgesic

• Known kidney disease

• Use of antidepressive