Effect of Peri-operative Glucocorticoids on Short-term Functional Outcome After THA
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
This randomized, single surgeon, placebo controlled, double blind study will be conducted in
order to investigate whether or not peri-operative high doses of intravenous glucocorticoids
improve short-term functional outcome after direct anterior total hip arthroplasty. So far,
it has been proven that high dose glucocorticoids reduce immediate post-operative pain and
nausea, but no data exists on functional outcome during the first 6 weeks. Our hypothesis is
that patients in the intervention group will follow a so-called "get ahead, stay ahead"
principle and that glucocorticoids can be considered an important tool (adjuvant treatment)
in the enhanced recovery pathway after THA with significant socio-economic implications.