Effect of Physical Activity on Neurogenesis in Peripheral Diabetic Neuropathy Type-II Diabetes
Status:
Not yet recruiting
Trial end date:
2025-03-31
Target enrollment:
Participant gender:
Summary
Approximately 425 million people worldwide suffer from diabetes, making it a global epidemic.
Diabetes consumes 12% of the global health budget, addressing the disease and its
complications. In Pakistan, the estimated prevalence of diabetes stands at 9.8%, affecting
both males and females. Diabetic peripheral neuropathy is a common complaint that
significantly impacts patients' quality of life. Neuropathy is prevalent in 40-55% of
diabetes cases, and its incidence rises with age. Additionally, exercise can promote
neurogenesis and the release of beneficial factors like BDNF, contributing to improved
cognitive function and mood. Aerobic exercises are recommended for managing type 2 diabetes,
while resistance training can improve glycemic control and muscle health. Further research is
needed to understand the effects of physical activity on neurogenesis in diabetic peripheral
neuropathy patients and gender-specific influences on glucose metabolism. The study aims to
enhance peripheral neurogenesis, glycemic control, and sensory functions, ultimately
improving the overall quality of life for patients.