Effect of Portal Vein Thrombosis on the Prognosis of Liver Cirrhosis
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
The prevalence of portal vein thrombosis (PVT) in patients with liver cirrhosis is 5-20%.
Current evidence regarding the effect of portal vein thrombosis on the prognosis of cirrhotic
patients remains under debate. Considering that PVT potentially elevates the portal pressure
and thereby increase the risk of variceal bleeding, we focus on the patients with high-risk
varices and variceal bleeding as the study population. Thus, the main goals are to analyze
the effect of PVT on the incidence of first variceal bleeding in patients without any prior
bleeding history but with high-risk varices, the incidence of recurrent variceal bleeding in
patients with a history of variceal bleeding, and the treatment failure rate of variceal
bleeding in patients with acute variceal bleeding. Certainly, the survival is also observed
in all patients.