Overview

Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients

Status:
Recruiting
Trial end date:
2022-07-01
Target enrollment:
0
Participant gender:
Female
Summary
Steep Trendelenburg positioning and insufflation of the abdominal cavity have shown to increase intra ocular pressure. Different anesthetic techniques can alter intra ocular pressure and a small pilot study showed decrease in Intraocular Pressure (IOP) in robotic case in steep Trendelenburg with IV anesthetics (TIVA). We want to quantify the degree of change in Intraocular Pressure (IOP) in female patients undergoing robotic procedures for cancer. We want to detect the difference in increase of pressure with total IV anesthesia versus conventional balanced anesthesia
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Florida
Treatments:
Anesthetics
Fentanyl
Lidocaine
Propofol
Rocuronium
Criteria
Inclusion Criteria:

- Females ≥ eighteen years of age

- Written informed consent obtained from the subject and the subject agrees to comply
with all the study-related procedures

- Subjects must be planning to receive robotic surgery for gynecological cancer or high
suspicion of cancer (these subject will be withdrawn if it his proven they don't have
cancer)

- Subjects must be cleared for surgery by the pre-anesthesia clinic

- All robotic GYN cancer patients 18 years of age and older with any preexisting medical
conditions that are deemed ready for surgery by the pre anesthesia clinic

Exclusion Criteria:

- Known increased intraocular pressure, prior eye surgery within a month, eye conditions
where the ophthalmologist would not allow an intra ocular pressure measurement

- Subjects with a previous treatment of diagnosis of increased intraocular pressure

- Subjects who have undergone eye surgery in the 30 days prior to consent

- Subjects for whom an ophthalmologist has determined cannot undergo intraocular
pressure measurement