Effect of Pregabalin Administration on Catheter- Related Bladder Discomfort in Urological Surgical Operations

• Status: Completed
• Trial end date: 2020-02-20
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to assess the effect of pregabalin administration on catheter-related bladder discomfort (CRBD). The study group includes patients that are about to be subjected to urological operations because of the high incidence of CRBD observed in this kind of surgical population.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Saint Savvas Anticancer Hospital
• Collaborator: University of Thessaly
• Treatments: Pregabalin

Criteria

Inclusion Criteria:

• All patients about to be subjected to urinary operations

• Signed informed consent

Exclusion Criteria:

• Preoperative urinary bladder/kidney dysfunction as a result of spinal cord pathology

• History of overactive ((urinary frequency>3 times at night and >8 times in 24 hours), neurogenic bladder

• End stage renal failure

• Central nervous system dysfunction

• Mental illness/ substance abuse

• Sensitivity to pregabalin

• Preoperative administration of pregabalin for other indications

• Recent bladder catheterization <3 months