Effect of Preoperative Intravenous Ferric Carboxymaltose for Clipping Surgery

• Status: Not yet recruiting
• Trial end date: 2023-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Hypothesis: Correction of preoperative anemia can reduce the need for intra-/postoperative RBC transfusions and can improve surgical outcomes.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Collaborator: Vifor Pharma

Criteria

Inclusion Criteria:

1. Adult patients: 19≤ age < 80

2. Patients with IDA (All of the following conditions must be met) A. Hb: female (10≤Hb<12g/dl), male (10≤Hb<13g/dl) B. Ferritin < 100ng/ml C. Transferrin saturation<20%

3. Patients with UIAs A. UIAs located in anterior circulation B. Size < 15mm C. Operable with clipping alone

Exclusion Criteria:

1. Age: <19, ≥80

2. Hb<10

3. Anemia except IDA A. Anaplastic anemia B. Hemolytic anemia C. Anemia with chronic disease

4. UIAs located in posterior circulation

5. Size of UIA ≥ 15mm

6. Not operable with clipping alone