Effect of Preoperative Oral Tramadol on Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis
Status:
Completed
Trial end date:
2021-02-28
Target enrollment:
Participant gender:
Summary
Aim: The purpose of this prospective, randomized, double-blind, controlled study was to
compare the preoperative oral tramadol medication with ibuprofen and acetaminophen on the
success of inferior alveolar nerve blocks (IANB) of mandibular posterior teeth in patients
experiencing symptomatic irreversible pulpitis.
Methodology: The study included five study groups, each consists of 50 patients who exhibited
symptomatic irreversible pulpitis of a mandibular first or second molar. The patients
received identically appearing capsules containing either tramadol 50 mg, tramadol 100 mg,
ibuprofen 600 mg, ibuprofen 600 mg/acetaminophen 1000 mg or placebo by mouth 60 min before
the administration of an IANB. Endodontic access was begun 15 min after completion of the
IANB, and all patients used for data analysis had profound lip numbness. The IANB success was
defined as no or mild pain (visual analog scale recordings) on pulpal access or
instrumentation. The data were analysed using chi-square χ2 and Kruskal-Wallis tests.