Effect of Preoperative Tamsulosin on Postoperative Urinary Retention
Status:
Not yet recruiting
Trial end date:
2024-08-01
Target enrollment:
Participant gender:
Summary
Approximately 25-30% of patients experience postoperative urinary retention after female
pelvic surgery with mid-urethral sling placement. These patients are discharged home with a
foley catheter for a few days. Despite being common, many patients consider being discharged
home with a foley catheter as a complication of surgery and as the worst part of their
experience. Previous studies have demonstrated that 3-5 days of preoperative tamsulosin (a
safe and low-cost medication) have been shown to improve postoperative urinary retention
rates. Although it takes tamsulosin 5 days to reach a steady-state in a patient, it reaches
peak blood volume in 4-5 hours in a fasting patient. The effect of a single dose of
preoperative tamsulosin on postoperative urinary retention has not been studied, however
would be substantially easier for patients than multiple days of preoperative doses. In this
study, the investigators would like to give patients preoperative tamsulosin versus placebo.
The investigators would then evaluate for postoperative urinary retention. Previous studies
have demonstrated a postoperative urinary retention rate decrease of 65-88% after various
tamsulosin protocols. However, the effect of single preoperative dose of tamusloin on
postoperative urinary retention has yet to be studied in female pelvic surgery. The
investigators hypothesize that a single preoperative dose of tamsulosin will decrease the
number of patients with postoperative urinary retention and therefore discharged with a foley
catheter. Our goal is to improve patient outcomes and satisfaction postoperatively.