Effect of Prilocaine on Motor Block During Caesarean Section

• Status: Completed
• Trial end date: 2024-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

To compare the effects of using intrathecal prilocaine combined with fentanyl on duration of motor block versus that of intrathecal bupivacaine combined with fentanyl in elective caesarean section.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Bupivacaine; Prilocaine

Criteria

Inclusion Criteria:

• Age (18-35)

• ASA II

• Singleton, full term pregnant females.

• Height (1.60-1.90) m.

• BMI > 35 kg m-2

• Scheduled for elective caesarean section under spinal anesthesia.

Exclusion Criteria:

• Patients requiring general anaesthesia

• Known or suspected coagulopathy (international normalised ratio > 1.4), thrombocytopenia (platelet count < 100,000).

• Known peripheral neuropathy, neurological deficits or skeletal deformities.

• Known allergy to prilocaine, bupivacaine , fentanyl.

• Infection at site of injection.

• Patients' refusal to sign informed consent

• Patients with uncontrolled cardiac morbidities (patients with tight valvular lesion, impaired contractility with ejection fraction less than 50%, heart block and arrhythmias), hypertensive disorders of pregnancy, peripartum bleeding.