Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus
Status:
Completed
Trial end date:
2019-12-20
Target enrollment:
Participant gender:
Summary
Glycemic control is naturally the principal topic of diabetes and complications that can be
developed as a consequence of loss of sensitivity to perceive insulin signals by the cell.
The glycemic control goals established by the ADA are: glycosylated hemoglobin (A1C) <7.0%,
fasting plasma glucose 80-130 mg/dL and casual plasma glycemia <180 mg/dL. The first-line
treatment in patients of recent diagnosis is metformin, however, studies have shown that
propolis, a resinous balsamic material collected by the Apis mellifera bee, from sprouts,
exudates of trees and other parts of the plants, represents a very important and promising
natural alternative in medicine, which can be considered as an antidiabetic agent.
The aim of this study is to evaluate the effect of propolis or metformin administration on
glycemic control in patients with type 2 Diabetes Mellitus without pharmacological treatment.
The investigators hypothesis is that propolis or metformin administration, modify the
glycemic control in patients with type 2 Diabetes Mellitus without pharmacological treatment.