Effect of Pyridoxine on Behavioral Adverse Events of Levetiracetam

• Status: Recruiting
• Trial end date: 2022-01-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is a two-arm parallel group randomized double-blind placebo-controlled trial with the aim of Investigating pyridoxine effect on behavioral side effects of levetiracetam in adult patients with epilepsy.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Nasim Tabrizi
• Collaborator: Mazandaran University of Medical Sciences
• Treatments: Pyridoxine

Criteria

Inclusion Criteria:

• Age≥18 years

• Patients with epilepsy

• Patients who are treated by levetiracetam (Levebel, Cobel darou) in recent month

• Complaint of behavioral problem

• Patient's consent for participation

Exclusion Criteria:

• History of known psychiatric disease

• Pregnancy

• Incidence of psychotic side effects including hallucination, psychosis, suicidal idea or attempt

• Treatment with psychiatric medications

• Alcohol or drug abuse

• Mental retardation to the degree that intervenes comprehension and response to questionnaire