Periodontitis is an immune-inflammatory disease affecting the supporting structures of the
teeth. It is a disease of multifactorial etiology, with microbial, genetic, environmental and
host factors involved, with the release of oxygen-free radicals by the inflammatory cells.
Quercetin, have shown potential antimicrobial activity, lowering of inflammatory markers,
cholesterol reduction and inhibiting bone loss. However, this data has largely been obtained
from in vitro and animal studies, but data from human studies are limited.