Effect of Rectal Misoprostol in Reducing Intra-operative Blood Loss During Myomectomy

• Status: Completed
• Trial end date: 2020-03-04
• Target enrollment: 0
• Participant gender: Female

Summary

A total of 200 women for elective abdominal myomectomy were randomly allocated into two groups.

100 women in experimental group were administered 400ug Misoprostol (2 tablets of Prosotec®) through the rectal route prior to surgery and 100 were in control group, in which no drug was administered.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pak Emirates Military Hospital
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

1. ASA physical status class I-II

2. Intramural or subserosal fibroids - diagnosed on ultrasound

3. Candidates for elective abdominal myomectomy

Exclusion Criteria:

1. Pre-operative Hemoglobin < 10 g/dl

2. Patient who received Danazol or GnRH analogues before surgery

3. No other systemic or metabolic disease