Effect of Reduction of Inflammatory Status on Glucose Metabolism in Overweight Men
Status:
Completed
Trial end date:
2005-07-01
Target enrollment:
Participant gender:
Summary
Overweight increases the risk to develop chronic diseases including type-2 diabetes and
cardiovascular disease. The low-grade inflammatory status often seen in overweight subjects
is thought to play an important role in disease development.
The purpose of this study is to determine the role of inflammation on glucose metabolism and
insulin resistance. In this study the effect of the anti-inflammatory treatment diclofenac on
markers of inflammation and on parameters of glucose metabolism will be studied.