Effect of Remote Ischemic Postcondioning on Glymphatic System in Acute Stroke

• Status: Not yet recruiting
• Trial end date: 2023-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Investigators aimed to investigate the changes of glymphatic function after remote ischemic postcondioning treatment in acute ischemic stroke .

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Affiliated Hospital of Xuzhou Medical University

Criteria

Inclusion Criteria:

• The patient was 18-80 years old;

• The NIHSS score was ≤ 25 and NIHSS > 5，Glasgow coma score ≥ 8;

• The patients were diagnosed as anterior circulation cerebral infarction and could start remote ischemic postcondioning within 24 hours after onset

• Normal to random time within 24 hours

• Written informed consent signed by patients or their families

Exclusion criteria:

• patients receiving thrombolysis or endovascular therapy;

• modified Rankin scale (mRS) score ≥ 2 before this attack;

• other intracranial lesions, such as cerebral hemorrhage, cerebral venous disease, severe subclavian artery stenosis and other diseases involving the brain;

• Arterial blood pressure ≤ 90/60mmHg or ≥ 180/100mmHg after treatment.