Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes

• Status: Completed
• Trial end date: 2007-11-01
• Target enrollment: 0
• Participant gender: All

Summary

This trial is conducted in the United States of America (USA). This trial compares the changes in HbA1c after 26 weeks of repaglinide and metformin fixed dose combination tablet given as twice daily versus three times daily regimens or versus twice daily rosiglitazone and metformin fixed dose combination tablet in subjects with type 2 diabetes currently on monotherapy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Novo Nordisk A/S
• Treatments: Metformin; Repaglinide; Rosiglitazone

Criteria

Inclusion Criteria:

• Type 2 diabetes for at least 3 months

• HbA1c between 7.5-11.0% on monotherapy or

• HbA1c between 7.0-10.0% on dual therapy

• BMI maximum 45 kg/m2

Exclusion Criteria:

• Any clinically significant disease history in the opinion of the investigator

• Severe heart disease

• Pregnancy