Effect of Rifampin on the Pharmacokinetics of Ixabepilone in Patients With Advanced Cancer

• Status: Completed
• Trial end date: 2008-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test how rifampin affects the removal of BMS-247550 (ixabepilone) from the body.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: R-Pharm
• Treatments: Epothilones; Rifampin

Criteria

Inclusion Criteria:

• Up to three prior chemotherapy regimens

• Measurable or non-measurable disease

• Available for treatment and follow-up

Exclusion Criteria:

• Neuropathy

• Uncontrolled cardiovascular disease

• Refusal to participate in genetic analysis