Effect of Rocuronium and Sugammadex Under Sevoflurane and Desflurane Anesthesia in Children
Status:
Completed
Trial end date:
2019-05-19
Target enrollment:
Participant gender:
Summary
Sugammadex is the first selective relaxant binding agent approved to reverse certain
non-depolarizing neuromuscular drugs in patients 2 years old and above. Although it has been
in use over the last 10 years, more pharmacological studies are needed to understand its
overall effects on participants.
As investigators' primary outcome, the investigators aimed to investigate how differently
sugammadex reverses neumuscular blockade caused by rocuronium under general anesthesia
maintenance with sevoflurane compared with desflurane. Also, to compare the changes in peak
airway pressure. As investigators' secondary outcome, the investigators aimed to compare the
changes in heart rate and blood pressures after sugammadex injection under sevoflurane and
desflurane general anesthesia.
Phase:
N/A
Details
Lead Sponsor:
Istanbul University
Collaborators:
Ayse Cigdem Tutuncu GAMZE PİRİNÇ ŞAŞIOĞLU GÜNER KAYA