Effect of Sedative Agent on Reducing the Frequency of Arrhythmia in the Patients After Cardiac Surgery

• Status: Completed
• Trial end date: 2019-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Arrhythmias early in the recovery period after cardio thoracic surgery are common they develop in 11 to 40 percent of patients after coronary-artery bypass grafting. The right chose of sedative agent could decrease the level of arrhythmia incidence.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Anesthesia Research Group UA
• Treatments: Dexmedetomidine; Propofol

Criteria

Inclusion Criteria:

• Multi vascular lesions of the coronary arteries according to coronary angiography;

• Heart valve damage was confirmed by heart ultrasound, which is subject to surgical correction (aortic stenosis of III degree with a gradient on the aortic valve of more than 42 mmHg, aortic insufficiency III, mitral valve stenosis II-III, mitral regurgitation II-III)

• Age of patients from 18-80 years;

Exclusion Criteria:

• Refusal to participate;

• Hypersensitivity to propofol, dexmedetomidine;

• Acute renal failure that occurred during surgery (ClCr less than 50 ml / h, or a decrease in the rate of diuresis to 0.1 ml / h in the first 4 hours after surgery and does not respond to diuretic therapy)