Effect of Sevoflurane and Remimazolam on Arterial Oxygenation During One-lung Ventilation

• Status: Recruiting
• Trial end date: 2024-06-30
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to compare the effect of sevoflurane and remimazolam on arterial oxygenation during one lung ventilation in patients undergoing video-assisted thoracoscopic surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pusan National University Yangsan Hospital
• Treatments: Propofol

Criteria

Inclusion Criteria:

• Patients undergoing video-assisted thoracoscopic surgery

• 19 years of age or older, less than 80 years old

• The American Society of Anesthesiologists (ASA) classification I-Ⅲ physical status

Exclusion Criteria:

• Patients with known allergy to benzodiazepine, propofol

• Patients with galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption

• Patients with hypersensitivity to Dextran40

• Patients with end stage renal disease requiring hemodialysis

• Patients with history of acute angle glaucoma

• Emergency operation

• Patients with unstable hemodynamics requiring inotropics

• Patients with preoperative oxygen supplement

• Preoperative forced expiratory volume (FEV1) less than 40% of predicted

• Preoperative ejection fraction less than 50%