Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure
Status:
Recruiting
Trial end date:
2024-10-01
Target enrollment:
Participant gender:
Summary
This is a multicenter, parallel-group, randomized, open-label, controlled trial. Patients
with a diagnosis of acute heart failure (AHF) in the emergency department (ED) or after
emergency presentation to hospital will be screened and informed of the study. After signed
consent, patients will be randomized into the control group (usual AHF treatment) or
intervention group (usual AHF treatment + prednisone). Prednisone will be given for 7 days.
Patients will be assessed at days 2, 4 or at discharge if earlier, and at day 7 at hospital
visit. If the patient has been discharged before day 7, a follow-up visit will be scheduled
at day 7 for endpoints assessment followed by a scheduled hospital visit at day 31 and a
telephone follow-up at day 91. Study drug will be dispensed for the patient to take home
until day 7.