Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic Sclerosis
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
Early phases of systemic sclerosis is characterized by inflammatory and microvasculature
alterations. Sildenafil citrate has been shown to have vasodilatory effects and to enhance
vasculogenesis. The purpose of this study is to evaluate the effect of sildenafil citrate on
hand blood flow of patients with systemic sclerosis, using Laser Doppler Imaging.
Phase:
Phase 3
Details
Lead Sponsor:
Federal University of São Paulo
Collaborator:
Fundação de Amparo à Pesquisa do Estado de São Paulo