Effect of Single-dose Dexmedetomidine on Airway Reflex in Adult With Oral Intubation After Thyroidectomy
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
Coughing during emergence from general anaesthesia may lead to dangerous effects including
laryngospasm, detrimental haemodynamic changes. Post-thyroidectomy bleeding occurs in 1-4% of
patients, and severe coughing may cause bleeding. Dexmedetomidine, a potent α adrenoreceptor
agonist, is theoretically appropriate for reducing airway and haemodynamic reflexes during
emergence from anaesthesia.
In this study, we investigated whether intravenous single-dose dexmedetomidine at the end of
surgery reduces coughing during extubation after thyroidectomy.