Effect of Sodium Bicarbonate on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Artery Bypass (OPCAB)

• Status: Completed
• Trial end date: 2015-10-20
• Target enrollment: 0
• Participant gender: All

Summary

In this single-site, randomized, controlled and double-blind clinical trial, the investigators evaluate the effect of sodium bicarbonate on prevention of acute kidney injury in high risk patients undergoing off pump coronary bypass surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University

Criteria

Inclusion Criteria:

• Patients older than 20 years

• scheduled for elective coronary artery bypass grafting.

• preoperative estimated glomerular filtration rate (eGFR) : 30 ~ 89 %

• LVEF < 35%

• NYHA class III or IV

• age > 70

• DM

• reoperation

Exclusion Criteria:

• acute renal impairment

• patients who receive dialysis

• patients who receive steroid ( > 10mg/day prednisolon or equivalent)

• hemo-alkalosis

• hypernatremia

• pulmonary edema

• Hemoglobin < 10 mg/dL