Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.
Status:
Not yet recruiting
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
The purpose of the study is to increase the in vivo levels of nitric oxide by generating
nitric oxide donor compound S-nitrosoacetylcysteine (SNOAC) using the mixture of sodium
nitrite and N-acetylcysteine crystals in the sublingual space. The generated SNOAC rapidly
diffuses into blood circulation thereby decrease the systemic blood pressure. This compound
can be an alternative to organic nitrate NO donor drugs without developing tolerance in
patients.